Cast
| Micah Abbey | Donatello |
| Shamon Brown Jr. | Michelangelo |
| Nicolas Cantu | Leonardo |
| Brady Noon | Raphael |
| Ayo Edebiri | April O'Neil |
| Jackie Chan | Master Splinter |
| Hannibal Buress | Genghis Frog |
| Rose Byrne | Leatherhead |
| John Cena | Rocksteady |
| Ice Cube | Superfly |
| Natasia Demetriou | Wingnut |
| Giancarlo Esposito | Baxter Stockman |
| Post Malone | Ray Fillet |
| Seth Rogen | Bebop, Producer, Screenwriter |
| Paul Rudd | Mondo Gecko |
| Maya Rudolph | Cynthia Utrom |
Crew
| Jeff Rowe | Director, Screenwriter |
| Kyler Spears | Co-Director |
| Seth Rogen | Bebop, Producer, Screenwriter |
| Evan Goldberg | Producer, Screenwriter |
| Dan Hernandez | Screenwriter |
| Benji Samit | Screenwriter |
| James Weaver | Producer |
| Ramsay McBean | Executive Producer |
| Josh Fagen | Executive Producer |
| Trent Reznor | Original Music |
| Atticus Ross | Original Music |
| Yashar Kassai | Production Design |
| Rich Delia | Casting |